Categories: Competition , Conferences |  Comments
Congratulations to all of our ISACS Chemistry World poster prize winners this year. Here’s a run-down of the winners:
Katie-Louise Finney, a second year PhD student in David Parker’s group at the University of Durham, UK, was the winner at ISACS 13 (Challenges in Inorganic and Materials Chemistry), held in Dublin, Ireland. Katie’s poster was titled ‘Development of 1H PARASHIFT probes for magnetic resonance spectroscopy and imaging‘.
Katie explains her work: ‘Our 1H PARASHIFT probes possess a tert-butyl reporter group that can be shifted well away from the water and fat signals at 4.7 and 1.3ppm. We have succeeded in shifting the tert-butyl reporter group as far as +65 and –75ppm. This means that in imaging experiments, we gain two orders of magnitude of sensitivity due to 1) the lack of background signal in vivo and 2) the enhanced reporter group relaxation by the proximal lanthanide ion. As a result, our probes have been imaged in live mice within minutes, at concentrations of 0.1mmol/kg.’
We’ve actually featured Katie’s MRI work in Chemistry World before in our article Moving the goalposts for MRI.